PE/Cyanine5 Anti-Rat CD45 Antibody [OX-1]

Size: 100μg

Catalogue Number: E-AB-F1227UG-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD45

Target Synonym: Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, LCA, T200, Ly-5, Ptprc,

Conjugation: PE/Cyanine5

Host: Mouse

Species Reactivity: Rat

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Isotype: Mouse IgG1, κ

Clone No.: OX-1

UNIProt ID: P04157

Background: CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets, isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells?in vitro.

Concentration: 0.2 mg/mL

Control Catalogue Number: E-AB-F09793G

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

GeneID: 19265

Storage: This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.

Shipping: Ice bag