K9 Advantix kills and repels fleas ticks mosquitoes biting flies and lice. Simpler than a flea collar and hard-to-swallow pills this topical formula works within 12 hours of initial application to stop existing flea infestations on dogs and prevent new ones by killing adult fleas on contact before they lay new eggs or bite your dog. K9 Advantix offers fast relief at an excellent value so you and your dog can get back to the things you love most. Your dog should be at least 7 weeks old and weigh 21-55 lbs. to use K9 Advantix Large Dog. Use as directed by label. Do not use on cats.