CD167a Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: NCP0289P-50, NCP0289P-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Swiss-Prot: Q08345

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: WB, IF

All Applications: WB: 1:1000~1:2000
IF 1:50~1:200

Background: Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CD167a polyclonal antibody detects endogenous levels of CD167a protein.

Bioworld Molecular Weight: ~ 95 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of CD167a polyclonal antibody at 1:1000 dilution
Lane 1: BV2 whole cell lysate (30ug)
Lane 2: PC12 whole cell lysate (30ug)
Lane 3: MCF-7 whole cell lysate (30ug)
Lane 4: A375 whole cell lysate (30ug)
Lane 5: HEK293T whole cell lysate (30ug), Immunofluorescence analysis of MCF-7 cells using CD167a pAb at dilution of 1:200.

Alternative Name: Epithelial discoidin domain-containing receptor 1; Epithelial discoidin domain receptor 1; CD167 antigen-like family member A; Cell adhesion kinase; Discoidin receptor tyrosine kinase; HGK2; Mammary carcinoma kinase 10; MCK-10; Protein-tyrosine kinase 3A; Protein-tyrosine kinase RTK-6; TRK E; Tyrosine kinase DDR; Tyrosine-protein kinase CAK; DDR1; CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE

Immunogen: Recombinant protein of human CD167a.

Conjugate: Unconjugated

Modification: Unmodified