Acetyl-p53 (Lys382) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16340-50, BZ16340-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P04637

Host: Rabbit

Reactivity: Human

Applications: WB,IHC-P,ELISA

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Background: Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Acetyl-p53 in HepG2Lysates using Acetyl-p53 antibody.

Bioworld Molecular Weight: Calculated MW: 44 kDa; Observed MW: 53 kDa

Specificity: IgG

Alternative Name: TP53; P53; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53

Immunogen: Synthesized acetyl-peptide derived from the human p53 around the acetylation site of K382.

Conjugate: Unconjugated

Modification: Acetylated