Benzyl-PEG9-Ots is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 393517-91-4

Molecular Weight: 658.80

Formula: C32H50O12S

Chemical Name: 1-phenyl-2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-yl 4-methylbenzene-1-sulfonate

Smiles: CC1C=CC(=CC=1)S(=O)(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCCOCC1C=CC=CC=1

InChiKey: LIXNLTAASAGPCK-UHFFFAOYSA-N

InChi: InChI=1S/C32H50O12S/c1-30-7-9-32(10-8-30)45(33,34)44-28-27-42-24-23-40-20-19-38-16-15-36-12-11-35-13-14-37-17-18-39-21-22-41-25-26-43-29-31-5-3-2-4-6-31/h2-10H,11-29H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.