LFR Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: GCP72-50, GCP72-100

Sizes: 50µl, 100µl

Swiss-Prot: Q8WWA0

Host: Rabbit

Reactivity: Human

Applications: WB, IHC

Background: Intelectin-1, also known as ITLN1, INTL, Omentin or LFR, is a 313 amino acid protein that contains one fibrinogen C-terminal domain and is either secreted or lipid-anchored to the cell membrane. Highly expressed in small intestine and adipose tissue and present at lower levels in testis, heart, pancreas, colon and skeletal muscle, Intelectin-1 exists as a disulfide-linked homotrimer that functions to enhance Insulin-stimulated glucose uptake and is also thought to participate in host defense against miccroorganisms. In addition to its roles in glucose regulation and immune system function, Intelectin-1 may also be involved in iron metabolism and obesity regulation in adults. Intelectin-2 shares 85% amino acid identity with Intelectin-1 and, like Intelectin-1, is a secreted protein that contains one fibrinogen C-terminal domain and is thought to play a role in the host defense system. While Intelectin-1 is present in a variety of tissues, Intelectin-2 exists only in the small intestine.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: LFR polyclonal antibody detects endogenous levels of LFR protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of LFR polyclonal antibody at 1:2000 dilution
Lane 1: A549 whole cell lysate (40ug)
Lane 2: HepG2 whole cell lysate (40ug), Immunohistochemistry of paraffin-embedded Human Colorectal cancer using LFR antibody at dilution of 1:50.

Bioworld Molecular Weight: ~ 34 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Intelectin-1; ITLN-1; Endothelial lectin HL-1; Galactofuranose-binding lectin; Intestinal lactoferrin receptor; Omentin

Immunogen: Synthetic peptide, corresponding to Human LFR.

Conjugate: Unconjugated

Modification: Unmodified