Propynyl-PEG1-Ac is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 944561-45-9

Molecular Weight: 158.15

Formula: C7H10O4

Chemical Name: 2-[2-(prop-2-yn-1-yloxy)ethoxy]acetic acid

Smiles: C#CCOCCOCC(O)=O

InChiKey: OFHMCWOCIIQXLU-UHFFFAOYSA-N

InChi: InChI=1S/C7H10O4/c1-2-3-10-4-5-11-6-7(8)9/h1H,3-6H2,(H,8,9)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.